Management Team
Jim Hopkins
Chief Executive Officer
Mr. Hopkins joined Tripos International in March of 2007. During the ten years prior to joining Tripos, Mr. Hopkins has been an executive officer or served on the boards of more than a dozen public and private companies. Most recently he was Chairman and CEO of Micrografx, Inc., a Texas-based Nasdaq-listed graphics software company that was sold to Corel Corporation. He became acquainted with Vector Capital while on the Board of Directors of Corel as a result of Vector’s purchase of Corel. He has taken companies through the IPO and Secondary public offering processes, and has conducted strategic acquisitions and sales of both public and private companies.
Patrick Flanagan
Chief Operating Officer and SVP, Consulting Services
Mr. Flanagan joined Tripos International in 2007, and currently leads both Pharsight and Tripos in his role as COO. He came to Tripos with a 15-year career in strategic sales and business development for leading companies in the healthcare, software, and consulting fields including Baxter International, Allegiance Healthcare, A.T. Kearney and Oracle. Mr. Flanagan holds a BS in Business from Penn State University and an MBA with a concentration in Finance and Marketing from the Kellogg Graduate School of Management at Northwestern University.
James Hayden
Senior Vice President, Global Sales and Marketing
Mr. Hayden has 15 years of experience in sales, marketing and management within the life sciences industry. Before joining Pharsight, Mr. Hayden was the National Director of Sales for Accelrys, Inc., a leading provider of software for computation, simulation, and the management and mining of scientific data used by biologists, chemists and materials scientists. While at Accelrys, he led a sales team responsible for major account sales of the company’s software solutions in the Americas region. In this role, he successfully reestablished the company’s presence in a failing geographical region and also developed a variety of sales infrastructure tools that allowed the company to gauge the progress of its sales team. Prior to this, he was a leading sales representative at Bio-Rad Laboratories, a developer of innovative tools and services for the clinical diagnostics and life sciences research markets. Mr. Hayden began his career as an electrical engineer at Raytheon and holds an MBA from Rutgers University and a B.S. in Electrical Engineering from Boston University.
Daniel L. Weiner, Ph.D.
Senior Vice President and General Manager, Software
Dr. Weiner has extensive drug development experience and has served as an expert consultant to the U.S. Food and Drug Administration (FDA) on pharmacokinetic modeling and bioequivalence assessment. Prior to his previous tenure with Pharsight as a Senior Vice President, Dr. Weiner held several management positions including Head, Biostatistics, Merrell Dow Pharmaceuticals; Vice President, Statistical Consultants, Inc.; Vice President, Syntex Development Research; Senior Vice President and Principal Scientist, Quintiles, and most recently, Senior Vice President and Global Head of Clinical Development at IVAX Research. Dr. Weiner graduated from the University of Kentucky with a doctoral degree in Mathematical Statistics, with emphasis on compartmental modeling, as well as an M.S. in Statistics, and a B.S. in Mathematics.
He is the co-author of Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications. Dr. Weiner is currently an Adjunct Associate Professor, Division of Pharmacotherapy and Experimental Therapeutics in the School of Pharmacy at the University of North Carolina, and a past Adjunct Associate Professor with the Colleges of Pharmacy and Environmental Health at the University of Cincinnati; a past President of the Greater Cincinnati Chapter of the American Statistical Association; a past Vice-Chair of the Biostatistics Subsection of PMA; and a past member of the Editorial Advisory Board for the Journal of Pharmaceutical Sciences.
John D. Yingling
Chief Financial Officer
Mr. Yingling joined Tripos International in March 2007. He received his B.S. degree in Accounting from the University of Missouri, St. Louis, in 1979 and holds certificates as a Certified Public Accountant and a Certified Cash Manager. Mr. Yingling worked for Storz Instrument Company, a micro-surgical instrument manufacturer, in a series of accounting positions from 1979 to 1983 and for Clayton Brokerage Company from 1983 to 1985. This was followed by several accounting, tax and treasury positions at Venture Stores, Inc. from 1985 to 1995. Mr. Yingling joined Tripos, Inc. in May 1995 as U.S. Controller and was promoted to Corporate Controller & Treasurer, then to Vice President, Chief Accounting Officer and ultimately to Chief Financial Officer in October, 2006.
Nancy Risch
Vice President, Global Sales
Ms. Risch, Vice President, Global Sales, has extensive experience in the software sales market, including both pharmaceutical and statistical data analysis. Prior to joining Pharsight, Ms. Risch was Eastern Region Director for BBN Corporation, where she was responsible for closing the largest sale in the history of the Manufacturing Division. While a Director of Worldwide Industry Sales at Interleaf, Ms. Risch was the only employee to achieve membership in the Golden Leaf Club 12 times. Prior to joining Interleaf, she also headed an Information Systems organization at General Electric Aircraft Engines. Ms. Risch began her software career at Wang. She majored in mathematics at West Virginia University.
JF Marier, Ph.D., FCP
Vice President and Lead Scientist, North America
Dr. Marier has directed PK/PD analyses, reporting, and modeling and simulation projects for hundreds of studies in early and late clinical research. His drug development experience spans noncompartmental and population PK/PD modeling and simulation across all phases of development and in specific populations (pediatric/geriatric, renal/liver impaired). His expertise includes scientific and regulatory consultation on drug development programs for small and large molecules, particularly in the therapeutics areas of oncology, inflammation, immunosuppressants, cardiovascular, infection and metabolic diseases. Dr. Marier has authored or co-authored more than 100 abstracts/manuscripts and book chapters in the field of PK/PD, and has leveraged modeling and simulation to build and optimize drug development programs for dozens of industry sponsors. Dr. Marier earned his Ph.D. in Pharmaceutical Sciences from the University of Montreal, Faculty of Pharmacy and is a fellow of the American College of Clinical Pharmacology.
Rene Bruno, Ph.D.
Managing Director, Consulting Services, Europe
Prior to joining Pharsight, Dr. Bruno spent the last three years at Genentech, Inc. in South San Francisco, Calif., where he was most recently senior scientist and head of the pharmacometry unit. Before Genentech, Dr. Bruno held various scientific research positions, including research advisor, over the course of 13 years at Rhone-Poulenc Rorer in Antony, France and Collegeville, Pa. Prior to Rhone-Polenc Rorer, Dr. Bruno was a pharmacokineticist at Syntex Research in France. To date, he has authored or co-authored more than 130 manuscripts and scientific communications in the field of drug development. Dr. Bruno has undertaken extensive work in the areas of modeling and simulation and has been an industry leader in supporting this methodology in the drug development process across several global projects. Dr. Bruno holds a Ph.D. in pharmacology from the University of Aix-Marseille, department of Pharmacokinetics and Toxicokinetics in School of Pharmacy. In addition, he holds a “Habilitation a des Recherches” from University of Aix-Marseille, the highest academic degree in France. Dr. Bruno held a “Maitre-Assistant” (Assistant Professor) position in the department of Pharmacokinetics and Toxicokinetics, School of Pharmacy, Marseilles before moving to the Pharmaceutical Industry.