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Using Phoenix Connect™ — Selected Examples

Here are several examples of the many ways you can use Phoenix Connect to interact with and manage third-party software tools to perform integrated analyses.

Analysis and Modeling with S-PLUS® and NONMEM®

Use Phoenix Connect to build a reusable analysis, modeling and reporting workflow:

  • Import data for analysis into Phoenix via Phoenix Connect
  • Process it with S-PLUS
  • Build preliminary plots using Phoenix’s native graphics
  • Fit base and covariate models using NONMEM
  • Bring the results back into the Phoenix workflow project
  • Use Phoenix Connect’s, SigmaPlot’s, and/or S-PLUS graphics to render the reuslts
  • Store results in the Phoenix project

Integrated Study Analysis with Phoenix™ WinNonlin® and PKS™

Phoenix Connect allows Phoenix WinNonlin users to work with the Pharsight Knowledgebase Server™ (PKS) for secure storage and change tracking for data and analyses.

  • Create a study in PKS from Phoenix
  • Use a subset of the data to create multiple model sets in one scenario using Phoenix WinNonlin (e.g., NCA, compartmental, bioequivalence, graphics, tables, descriptive statistics)
  • Save all results back into PKS
  • If you update or change the data in the study, the scenario in PKS can be refreshed into a new version in one easy step.

NCA Analysis and Post-Processing with SAS®

Use Phoenix WinNonlin’s noncompartmental analysis (NCA) engine to compute derived measurements from raw data and then do post-processing in SAS or S-PLUS.

  • Import SAS dataset into Phoenix via Phoenix Connect
  • Use a SAS program from within Phoenix to perform data manipulation
  • Use the results from SAS to perform NCA analysis with Phoenix WinNonlin
  • Perform additional post-processing in SAS
  • If you change the source or derived data in SAS or Phoenix, the analysis can be refreshed in one step since all steps are contained in a Phoenix project that can be easily shared with others.

Flexibility is the key word that describes what Phoenix Connect provides. It helps break down the barriers between systems and enhances productivity through increased interoperability.