Related Resources
®Clinical Utility Index (CUI®) Analysis — Selected References
Journal Articles
Carrothers TJ, Hodge FL, Korsan RJ, Poland WB, Dykstra KH. Decision-Making in Drug Development: Application of a Clinical Utility Index. In Kimko HC, Peck CC (Eds). Clinical Trial Simulations: Applications and Trends. AAPS Advances in the Pharmaceutical Sciences Series, Vol. 1. ISBN: 978-1-4419-7414-3. Available: November 2010.
Poland B, Hodge FL, Khan A, Clemen RT, Wagner JA, Dykstra K, Krishna R. The Clinical Utility Index as a Practical Multiattribute Approach to Drug Development Decisions. Clin Pharmacol Ther advance online publication, May 20, 2009; doi:10.1038/clpt.2009.71.
Korsan B, Dykstra K, Pullman W. Transparent Trade-Offs: A Clinical Utility Index (CUI) Openly Evaluates a Product's Attributes ? and Chance of Success. Pharmaceutical Executive. March 2005.
Presentations and Posters
Carrothers TJ. The Clinical Utility Index, a Method for Balancing Efficacy and Safety in Drug Development Decision-Making. [invited presentation]. Presented at: Pacific Coast Statisticians & Pharmacometricians Innovation Conference (PaSiPhIC); June 14-16, 2010; San Luis Obispo, CA.
Hodge FL. Using the Clinical Utility Index (CUI) to Inform Dose Selection Decisions: Integrated Modeling and Simulation Approach in Alzheimer's Disease. Pharsight Webinar; February 4, 2009.
Dykstra K, Hodge L, Carrothers TJ, Korsan B. Linking Modeling & Simulation, Decision Analysis, and the Technology of Drug Formulation. [poster #67]. American Conference on Pharmacometrics (ACoP); March 9-12, 2008; Tucson, Arizona.