Selected Cardiovascular References
Journal Articles
Rohatagi S, Carrothers T, Kshirsagar S, Khariton T, Lee J, Salazar D. Evaluation of Population Pharmacokinetics and Exposure-Response Relationship With Coadministration of Amlodipine Besylate and Olmesartan Medoxomil. J Clin Pharm OnlineFirst, published on May 19, 2008 as doi:10.1177/0091270008317847.
Mandema JW, Hermann D, Wang W, Sheiner T, Milad M, Bakker-Arkema R, Hartman D. Model-Based Development of Gemcabene, a New Lipid-Altering Agent. AAPS Journal. 2005; 7(3).
Kazutaka Y, Gao Y, Shiga H, Wada DR, Hisaoka M. Population Pharmacokinetics of Olmesartan Following Oral Administration of its Prodrug, Olmesartan Medoxomil: In Healthy Volunteers and Hypertensive Patients. Clinical Pharmacokinetics. 2005; Volume 44, Number 12; pp. 1329-1342(14).
Conference Presentations & Posters
Rohatagi S, Carrothers T, Kshirsagar S, Khariton T, Lee J, Salazar D. Evaluation of Population (POP) Pharmacokinetics (PK) after Coadministration of Olmesartan Medoxomil (OM) and Amlodipine Besylate (AM), [poster P-429]. Presented at: Amercian Society of Hypertension 22nd Annual Scientific Meeting and Exposition; May 19-22, 2007; Chicago, Illinois.
Hermann D, Wang W, Falcoz C, Hartman D, Mandema J. Strategies to Improve Model-Based Decision-Making During Clinical Development [poster]. Presented at: Annual Meeting of the Population Approach Group in Europe (PAGE); June 2005; Pamplona, Spain. Reprinted courtesy of PAGE.