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Selected Case Examples of QTc Modeling and Simulation

Role of Modeling and Simulation in Evaluating the QTc Prolongation Potential of Drugs (presented at ACoP 2008)

  • Case 1: Phase II Dose Selection
  • Case 2: Pre-clinical to Clinical
  • Case 3: Individual QT Correction
  • Case 4: Agreement with TQT
  • Case 5: Anti-coagulant
  • Case 6: Anti-diabetic Agent
  • Case 7: Anti-platelet Agent