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Training Courses and Workshops

Course Description: Advanced PK/PD Modeling Methodology using Phoenix WinNonlin
Course Description: An Introduction to the Design, Role and Utility of Pharmacokinetics and Pharmacodynamics in Drug Development
Course Description: IVIVC Toolkit for WinNonlin v5 - In Vivo-In Vitro Correlations
Course Description: Intermediate PK/PD Modeling Methodology Using Phoenix WinNonlin
Course Description: Introduction to Phoenix WinNonlin
Course Description: Phoenix NLME - A Next Generation Tool for Population PK/PD Analysis
Course Description: Population Modeling Methodology using Phoenix NLME
Course Description: Transitioning to Phoenix NLME - for experienced population modelers
Course Description: Transitioning to Phoenix WinNonlin - for existing WinNonlin Users
Course Description: Trial Simulator Hands-On v2.2.1
Course Description: WinNonlin Hands-on v5


Current Course Offerings

No such courses are being offered at this time, however, you can request it be added. As soon as there's enough demand for this course, the course will be scheduled and you will be informed of the course date.


Course Description

Title Phoenix NLME - A Next Generation Tool for Population PK/PD Analysis
Description / Agenda / Objectives This hands-on workshop will give participants an opportunity to become familiar with Phoenix NLME, a next generation nonlinear mixed effects modeling product. Instruction will be given on basic data management and exploratory graphical and tabular data analysis methods, as well as model building, comparison and evaluation of methods for nonlinear mixed effects modeling. Using the integral Phoenix Connect function, attendees will be able to include NONMEM, SAS and S-Plus scripts in graphical workflows along with Phoenix NLME.

Agenda

Overview of Basic Phoenix Platform Functionality

  • Importing data
  • Basic data management
  • Graphical summaries including lattice plots
  • Creating workflows

Population PK/PD Modeling

  • Building a base model via model libraries, the graphical model builder (Phoenix writes the corresponding model code automatically) and via the Phoenix modeling language
  • Strategies for covariate selection (shotgun approach, user specified scenarios and forward selection/backward elimination)
  • Use of Phoenix Model Comparison tool to aid selection of the best model
  • Interpretation of standard model output including diagnostic plots (including CWRES and other diagnostic plots) and model fitting summaries
  • Bootstrap and posterior predictive checks

Using Phoenix Connect

  • Using S-Plus and SAS to pre- and post-process data files and model results
  • Using NONMEM control files in Phoenix workflows
Prerequisites None.